HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl morpholine oxide → 5-Phenyl-1-(phenylsulfonyl)-4-propyl-1H-pyrrole-3-carbaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl morpholine oxide | HCID 82029 | — |
| Reactant | [5-Phenyl-1-(phenylsulfonyl)-4-propyl-1H-pyrrol-3-yl]methanol | HCID 66925059 | — |
| Catalyst | HCID 178419074 | HCID 178419074 | — |
| Product | 5-Phenyl-1-(phenylsulfonyl)-4-propyl-1H-pyrrole-3-carbaldehyde | HCID 86232864 | 49% |
Reaction Steps
Using [5-phenyl-1-(phenylsulfonyl)-4-propyl-1H-pyrrol-3-yl]methanol (2.73 g), tetra-n-propylammonium perruthenate (142 mg), N-methylmorpholine N-oxide (1.04 g) and molecular sieves 4A powder (1.5 g), a procedure as in Reference Example 6 was performed to give the title compound as a pale-red oil (yield 1.33 g, 47%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08048909B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-e39546c113504f6094a4e5b54693eae1 |
| Source note | uspto-grants-2011_11 |