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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 554307Generated: October 28, 2026

Methyl morpholine oxide → 5-Phenyl-1-(phenylsulfonyl)-4-propyl-1H-pyrrole-3-carbaldehyde

https://huagongshe.com/reaction/554307

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl morpholine oxideHCID 82029—
Reactant[5-Phenyl-1-(phenylsulfonyl)-4-propyl-1H-pyrrol-3-yl]methanolHCID 66925059—
CatalystHCID 178419074HCID 178419074—
Product5-Phenyl-1-(phenylsulfonyl)-4-propyl-1H-pyrrole-3-carbaldehydeHCID 8623286449%

Reaction Steps

Using [5-phenyl-1-(phenylsulfonyl)-4-propyl-1H-pyrrol-3-yl]methanol (2.73 g), tetra-n-propylammonium perruthenate (142 mg), N-methylmorpholine N-oxide (1.04 g) and molecular sieves 4A powder (1.5 g), a procedure as in Reference Example 6 was performed to give the title compound as a pale-red oil (yield 1.33 g, 47%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08048909B2
Source datasetuspto-grants-2011_11
ORD IDord-e39546c113504f6094a4e5b54693eae1
Source noteuspto-grants-2011_11