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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 554475Generated: October 30, 2026

6-hydroxy-2H-chromen-2-one → 6-(3-Aza-spiro[5.5]undec-9-yloxy)-chromen-2-one

https://huagongshe.com/reaction/554475

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-hydroxy-2H-chromen-2-oneHCID 99477—
Reactanttert-Butyl 9-hydroxy-3-azaspiro[5.5]undecane-3-carboxylateHCID 66701044—
Product6-(3-Aza-spiro[5.5]undec-9-yloxy)-chromen-2-oneHCID 16006549—

Reaction Steps

Was prepared according to method A from 6-hydroxycoumarin and 9-hydroxy-3-aza-spiro[5.5]undecane-3-carboxylic acid tert-butyl ester. Mp. 192.9-193.6° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08049012B2
Source datasetuspto-grants-2011_11
ORD IDord-a28ddcbfa0d14798a690decd4a26cffc
Source noteuspto-grants-2011_11