Cyclopropanecarbonyl chloride → HCID 67213056, compound

HRID 554591Notes

Reaction equation

HRID 554591 reaction equation
[CH2:1]([NH:8][CH2:9][C:10]1[CH:11]=[C:12]([CH:15]=[CH:16][C:17]=1[Br:18])[C:13]#[N:14])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH:19]1([C:22](Cl)=[O:23])[CH2:21][CH2:20]1>>[CH2:1]([N:8]([CH2:9][C:10]1[CH:11]=[C:12]([C:13]#[N:14])[CH:15]=[CH:16][C:17]=1[Br:18])[C:22]([CH:19]1[CH2:21][CH2:20]1)=[O:23])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 77637Cyclopropanecarbonyl chlorideHCID 67212465HCID 67212465, compound

Product 1

HCID 67213056HCID 67213056, compound

Procedure

3-(Benzylamino-methyl)-4-bromo-benzonitrile and cyclopropanecarbonyl chloride were reacted as described in Example 2, Step 3 to provide cyclopropanecarboxylic acid benzyl-(2-bromo-5-cyano-benzyl)-amide.

Sources & evidence

ORD record
ord-39dec98f1c3d4738b25ce51c68356384
Source dataset
uspto-grants-2011_11
Patent number
US08049015B2

Reaction notes

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