Tert-Butylamine → HCID 67212537, compound
Reaction equation
[CH2:1]([N:8]([CH2:14][C:15]1[CH:16]=[C:17]([CH:21]=[CH:22][C:23]=1[Br:24])[C:18]([OH:20])=O)[C:9]([CH:11]1[CH2:13][CH2:12]1)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:25]([NH2:29])([CH3:28])([CH3:27])[CH3:26]>>[CH2:1]([N:8]([CH2:14][C:15]1[CH:16]=[C:17]([CH:21]=[CH:22][C:23]=1[Br:24])[C:18]([NH:29][C:25]([CH3:28])([CH3:27])[CH3:26])=[O:20])[C:9]([CH:11]1[CH2:12][CH2:13]1)=[O:10])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1Participants
3
Procedure
3-[(N-Benzyl-N-cyclopropanecarbonyl-amino)-methyl]-4-bromo-benzoic acid and tert-butylamine were reacted as described in Example 5, Step 6 to provide 3-[(N-benzyl-N-cyclopropanecarbonyl-amino)-methyl]-4-bromo-N-tert-butyl-benzamide
Sources & evidence
- ORD record
- ord-b09f8dd83f9349ab9c0b22fc086b531b
- Source dataset
- uspto-grants-2011_11
- Patent number
- US08049015B2
Reaction notes
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