HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 2-(5-bromopyridin-3-yl)acetate → [5-(2-Formyl-4-trifluoromethyl-phenyl)-pyridin-3-yl]-acetic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 2-(5-bromopyridin-3-yl)acetate | HCID 23398394 | — |
| Reactant | 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)benzaldehyde | HCID 86640534 | — |
| Product | [5-(2-Formyl-4-trifluoromethyl-phenyl)-pyridin-3-yl]-acetic acid methyl ester | HCID 86640539 | — |
Reaction Steps
2-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-5-trifluoromethyl-benzaldehyde and (5-bromo-pyridin-3-yl)-acetic acid methyl ester were reacted as described in Example 8, Step 4 to provide [5-(2-formyl-4-trifluoromethyl-phenyl)-pyridin-3-yl]-acetic acid methyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08049015B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-3dad0b261ff64a65b904de5fdf7699bf |
| Source note | uspto-grants-2011_11 |