Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 554638Generated: October 31, 2026

Cyclopropanecarboxylic acid → (5-{2-[(N-Cyclopropanecarbonyl-N-ethyl-amino)-methyl]-4fluoro-phenyl}-pyridin-3-yl)-acetic acid ethyl ester

https://huagongshe.com/reaction/554638

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopropanecarboxylic acidHCID 15655—
Reactant[5-(2-Ethylaminomethyl-4-fluoro-phenyl)-pyridin-3-yl]-acetic acid ethyl esterHCID 58565094—
Product(5-{2-[(N-Cyclopropanecarbonyl-N-ethyl-amino)-methyl]-4fluoro-phenyl}-pyridin-3-yl)-acetic acid ethyl esterHCID 58565012—

Reaction Steps

[5-(2-Ethylaminomethyl-4-fluoro-phenyl)-pyridin-3-yl]-acetic acid ethyl ester and cyclopropanecarboxylic acid were reacted as described in Example 8, Step 6 to provide (5-{2-[(N-cyclopropanecarbonyl-N-ethyl-amino)-methyl]-4-fluoro-phenyl}-pyridin-3-yl)-acetic acid ethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08049015B2
Source datasetuspto-grants-2011_11
ORD IDord-683f2bc3189c481b8da77fe66dd7a668
Source noteuspto-grants-2011_11