N-Methylbenzylamine → HCID 57670970, compound

HRID 554772Notes

Reaction equation

[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([O:30][CH3:31])=[C:6]([CH:29]=1)/[CH:7]=[C:8]1\[CH2:9][N:10]([CH3:28])[C:11](=[O:27])[CH2:12][N:13]([C:16]([NH:18][C@@H:19]([C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)C)=[O:17])[C:14]\1=[O:15].[C:32]1([C@H](N)C)C=CC=CC=1.CNCC1C=CC=CC=1>>[CH2:19]([N:18]([CH3:32])[C:16]([N:13]1[C:14](=[O:15])/[C:8](=[CH:7]/[C:6]2[CH:29]=[C:2]([Cl:1])[CH:3]=[CH:4][C:5]=2[O:30][CH3:31])/[CH2:9][N:10]([CH3:28])[C:11](=[O:27])[CH2:12]1)=[O:17])[C:21]1[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=1

Participants

Reactant 3

HCID 7669N-Methylbenzylamine

HCID 6431891-Phenethylamine, (+)-

HCID 57671125HCID 57671125, compound

Product 1

HCID 57670970HCID 57670970, compound

Procedure

Instead of the starting material compound of Example 27, that is, (R)-(+)-1-phenylethylamine, N-methylbenzylamine was used for the similar procedure as with Example 27 to obtain the title compound.

Sources & evidence

ORD record: ord-493e67c00baf4800aa238983f886a770
Source dataset: uspto-grants-2011_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08049006B2

Reaction notes

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