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HRID 554894作成日：2026年10月25日

Ethyl 2-(3-(2-(4-fluorobenzylamino)-2-oxoethyl)-2-oxoimidazolidin-1-yl)-4-methylthiazole-5-carboxylate → 4-Methyl-2-(3-(2-(methylamino)-2-oxoethyl)-2-oxoimidazolidin-1-yl)thiazole-5-carboxylic acid

https://huagongshe.com/reaction/554894

反応式

関与物質

役割名称HCID仕込み量
反応物Ethyl 2-(3-(2-(4-fluorobenzylamino)-2-oxoethyl)-2-oxoimidazolidin-1-yl)-4-methylthiazole-5-carboxylateHCID 57919793—
反応物Ethyl 4-methyl-2-(3-(2-(methylamino)-2-oxoethyl)-2-oxoimidazolidin-1-yl)thiazole-5-carboxylateHCID 57919879—
生成物4-Methyl-2-(3-(2-(methylamino)-2-oxoethyl)-2-oxoimidazolidin-1-yl)thiazole-5-carboxylic acidHCID 57919952—

反応手順

Following the procedure as described in Preparation 9, making variations as required to replace ethyl 2-(3-(2-(4-fluorobenzylamino)-2-oxoethyl)-2-oxoimidazolidin-1-yl)-4-methylthiazole-5-carboxylate with ethyl 4-methyl-2-(3-(2-(methylamino)-2-oxoethyl)-2-oxoimidazolidin-1-yl)thiazole-5-carboxylate, the crude title compound was obtained.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08049016B2
出典データセットuspto-grants-2011_11
ORD IDord-43be7a7ca8344eb68bcabc84989f1b6d
出典メモuspto-grants-2011_11