Trimethylsilyldiazomethane → HCID 135814503, compound

HRID 555260Notes

Reaction equation

[Br:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]=[C:7]([C:12]([CH3:14])=[CH2:13])[NH:6][C:5]2=[O:15].[Si]([CH:20]=[N+:21]=[N-:22])(C)(C)C>>[Br:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]=[C:7]([C:12]1([CH3:14])[CH2:13][CH:20]=[N:21][NH:22]1)[NH:6][C:5]2=[O:15]

Participants

Reactant 2

HCID 167693Trimethylsilyldiazomethane

HCID 135814507HCID 135814507, compound

Product 1

HCID 135814503HCID 135814503, compound

Procedure

Following the procedure described in the Example 7, using 6-bromo-2-isopropenyl-3H-quinazolin-4-one and TMSCHN2 as starting materials to yield the title compound as a white solid.

Sources & evidence

ORD record: ord-0e888bdbcff34c28945da2903c52e660
Source dataset: uspto-grants-2011_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08053441B2

Reaction notes

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