Trimethylsilyldiazomethane → HCID 135779826, compound

HRID 555261Notes

Reaction equation

HRID 555261 reaction equation
[C:1]([C:4]1[NH:13][C:12](=[O:14])[C:11]2[C:6](=[CH:7][C:8]([C:15]([F:18])([F:17])[F:16])=[CH:9][CH:10]=2)[N:5]=1)([CH3:3])=[CH2:2].[Si]([CH:23]=[N+:24]=[N-:25])(C)(C)C>>[CH3:2][C:1]1([C:4]2[NH:13][C:12](=[O:14])[C:11]3[C:6](=[CH:7][C:8]([C:15]([F:17])([F:18])[F:16])=[CH:9][CH:10]=3)[N:5]=2)[CH2:3][CH:23]=[N:24][NH:25]1

Participants

3

Reactant 2

HCID 167693TrimethylsilyldiazomethaneHCID 135814502HCID 135814502, compound

Product 1

HCID 135779826HCID 135779826, compound

Procedure

Following the procedure in Example 7, using 2-isopropenyl-7-trifluoromethyl-3H-quinazolin-4-one and TMSCHN2 as starting materials yielded the title compound as a white solid.

Sources & evidence

ORD record
ord-7ac8ead4dbe74bebab87ca8db9d7882f
Source dataset
uspto-grants-2011_11
Patent number
US08053441B2

Reaction notes

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