HuagongsheHuagongshe Chemistry Print Report · For research reference only
Anthranilamide → HCID 136038001, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Anthranilamide | HCID 6942 | — |
| Reactant | 4-(N,N-Bis(2-hydroxyethyl)amino)benzaldehyde | HCID 12824965 | — |
| Reactant | 5,7-dimethoxy-2-(pyridin-2-yl)quinazolin-4(3H)-one | HCID 136037998 | — |
| Product | HCID 136038001 | HCID 136038001 | 42% |
Reaction Steps
2-(4-(Bis(2-hydroxyethyl)amino)phenyl)quinazolin-4(3H)-one was synthesized from anthranilamide and 4-[bis-(2-hydroxy-ethyl)-amino]-benzaldehyde, using the method described for 5,7-dimethoxy-2-(pyridin-2-yl)quinazolin-4(3H)-one. 2-(4-(Bis(2-hydroxyethyl)amino)phenyl)quinazolin-4(3H)-one (150 mg, 42%) was isolated as a brown solid. Selected data: MS (m/z): 326.03; MP 228-230° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08053440B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-70adafc92d9845ed9d1e34f338dd0aae |
| Source note | uspto-grants-2011_11 |