Hydrochloric Acid → HCID 46193615, compound

HRID 555648Notes

Reaction equation

HRID 555648 reaction equation
[CH2:1]([N:8]1[C:12]2[CH:13]=[CH:14][Se:15][C:11]=2[C:10]([C:16]2[O:17][C:18]([C:21]([O:23]C)=[O:22])=[CH:19][CH:20]=2)=[N:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl>[OH-].[Na+]>[CH2:1]([N:8]1[C:12]2[CH:13]=[CH:14][Se:15][C:11]=2[C:10]([C:16]2[O:17][C:18]([C:21]([OH:23])=[O:22])=[CH:19][CH:20]=2)=[N:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 46193500HCID 46193500, compound

Product 1

HCID 46193615HCID 46193615, compoundYield 80.2%

Reagents, catalysts & solvents 1

HCID 14798Sodium HydroxideSolvent

Procedure

Compound 55 (0.772 g, 0.002 mole) in 20 ml of 10% NaOH solution was heated under refluxing for 2 h, cooled and acidified with 10% HCl solution in an icewater bath. The precipitates were collected, then recrystallized from ethanol to afford compound 59 (0.595 g). Yield 80.2%; white crystals; mp 243-244° C.

Workup

  1. temperatureunder refluxing for 2 h
  2. temperaturecooled
  3. customThe precipitates were collected
  4. customrecrystallized from ethanol

Sources & evidence

ORD record
ord-8d183e4104db49dd8306b54f5b5bc953
Source dataset
uspto-grants-2011_11
Patent number
US08053459B1

Reaction notes

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