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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 555740Generated: October 26, 2026

Bromoacetonitrile → 2-(4-Benzylpiperazin-1-yl)acetonitrile

https://huagongshe.com/reaction/555740

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBromoacetonitrileHCID 11534—
Reactant1-BenzylpiperazineHCID 75994—
Product2-(4-Benzylpiperazin-1-yl)acetonitrileHCID 3855721—

Reaction Steps

The title compound is synthesized by coupling of 1-Benzyl-piperazine and bromoacetonitrile analogously to the preparation of Intermediate 149.2 as a white solid; ES-MS: M+=216.2: AtRet=1.50.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08053457B2
Source datasetuspto-grants-2011_11
ORD IDord-95091fe7372a44b8a90fa6737f844031
Source noteuspto-grants-2011_11