HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromoacetonitrile → (4-Cyclopentyl-piperazin-1-yl)-acetonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromoacetonitrile | HCID 11534 | — |
| Reactant | 1-Cyclopentylpiperazine | HCID 806421 | — |
| Product | (4-Cyclopentyl-piperazin-1-yl)-acetonitrile | HCID 60750841 | — |
Reaction Steps
The title compound is synthesized by coupling of 1-Cyclopentyl-piperazine (commercially available from CHESS GmbH) and bromoacetonitrile analogously to the preparation of Intermediate 149.2 as a colorless oil; ES-MS: M+=194.2: 1HNMR(DMSO-d6) 3.65 (s, 2H), 2.45-2.20 (m, 9H), 1.80-1.20 (m, 8H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08053457B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-9c080a3a1b2a4b4b9f6eb6ed27ac5cf5 |
| Source note | uspto-grants-2011_11 |