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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 555748Generated: October 31, 2026

Bromoacetonitrile → HCID 86641789, compound

https://huagongshe.com/reaction/555748

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBromoacetonitrileHCID 11534—
Reactant4-(1-Pyrrolidinyl)piperidineHCID 78703—
ProductHCID 86641789HCID 86641789—

Reaction Steps

The title compound is synthesized by coupling of 4-Pyrrolidin-1-yl-piperidine (commercially available from CHESS GmbH) and bromoacetonitrile analogously to the preparation of Intermediate 149.2 as a white solid; ES-MS: M+=194.1: 1HNMR(DMSO-d6) 3.65 (s, 2H), 2.75-2.70 (m, 2H), 2.45-2.40 (m, 4H), 2.20-2.10 (m, 2H), 1.90-1.75 (m, 3H), 1.65-1.60 (m, 4H), 1.45-1.30 (m, 2H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08053457B2
Source datasetuspto-grants-2011_11
ORD IDord-89d57211dbe543e3aefbc270fb639470
Source noteuspto-grants-2011_11