HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromoacetonitrile → (4-Adamantan-1-yl-piperazin-1-yl)-acetonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromoacetonitrile | HCID 11534 | — |
| Reactant | Piperazine, 1-(1-adamantyl)- | HCID 35373 | — |
| Product | (4-Adamantan-1-yl-piperazin-1-yl)-acetonitrile | HCID 84083703 | — |
Reaction Steps
The title compound is synthesized by coupling of 1-Adamantyl-piperazine (commercially available from CHESS GmbH) and bromoacetonitrile analogously to the preparation of Intermediate 149.2 as a colorless oil; ES-MS: M+=260.3: 1HNMR(DMSO-d6) 3.65 (s, 2H), 2.60-2.50 (m, 4H), 2.45-2.40 (m, 4H), 2.00 (bs, 3H), 1.60-1.50 (m, 12H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08053457B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-99a1dbb36f5348458110d9cde561c6c1 |
| Source note | uspto-grants-2011_11 |