HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromoacetonitrile → (4-Indan-1-yl-piperazin-1-yl)-acetonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromoacetonitrile | HCID 11534 | — |
| Reactant | 1-Indan-1-yl-piperazine | HCID 10845802 | — |
| Product | (4-Indan-1-yl-piperazin-1-yl)-acetonitrile | HCID 86641798 | — |
Reaction Steps
The title compound is synthesized by coupling of 1-Indan-1-yl-piperazine (commercially available from CHESS GmbH) and bromoacetonitrile analogously to the preparation of Intermediate 149.2 as a colorless oil; ES-MS: M+H=242.2: CtRet=4.25.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08053457B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-4e927e96c23c49c6ae3fdb6766f989c0 |
| Source note | uspto-grants-2011_11 |