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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 555776Generated: October 26, 2026

Bromoacetonitrile → (4-Phenethyl-piperazin-1-yl)-acetonitrile

https://huagongshe.com/reaction/555776

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBromoacetonitrileHCID 11534—
Reactant1-PhenethylpiperazineHCID 79214—
Product(4-Phenethyl-piperazin-1-yl)-acetonitrileHCID 55026723—

Reaction Steps

The title compound is synthesized by coupling of 4-Phenylethyl-piperazine (commercially available from ABCR GmbH) and bromoacetonitrile analogously to the preparation of Intermediate 149.2 as a colorless oil; ES-MS: M+H=230.2: CtRet=4.20.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08053457B2
Source datasetuspto-grants-2011_11
ORD IDord-21817461be514e7eafe8ee03d669d6e8
Source noteuspto-grants-2011_11