HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pivalaldehyde → HCID 16748909, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pivalaldehyde | HCID 12417 | — |
| Reactant | tert-Butyl piperazine-1-carboxylate | HCID 143452 | — |
| Solvent | Dichloromethane ethylacetate | HCID 21226138 | — |
| Product | HCID 16748909 | HCID 16748909 | — |
Reaction Steps
The title compound is synthesized by reductive amination of 1-Boc-piperazine and Pivalaldehyde analogously to the preparation of Example 233 as a colorless oil; ES-MS: M+H=257.3; TLC: Rf=0.82 (DCM/EtOAc=4:1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08053457B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-f96fdcfa13c14e23a06156d34a1ff251 |
| Source note | uspto-grants-2011_11 |