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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 555981Generated: November 1, 2026

2-(2-Ethyl-2h-tetrazol-5-yl)-ethylamine → 1-(6-Bromo-imidazo[1,2-a]pyridin-2-yl)-3-[2-(2-ethyl-2h-tetrazol-5-yl)-ethyl]-urea

https://huagongshe.com/reaction/555981

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(2-Ethyl-2h-tetrazol-5-yl)-ethylamineHCID 55285500—
Reactant1-(6-Bromo-imidazo[1,2-a]pyridin-2-yl)-3-[2-(2-isopropyl-2H-tetrazol-5-yl)-ethyl]-ureaHCID 59251873—
Reactant2-(2-isopropyl-2H-tetrazol-5-yl)-ethylamine hydrochlorideHCID 66986243—
Product1-(6-Bromo-imidazo[1,2-a]pyridin-2-yl)-3-[2-(2-ethyl-2h-tetrazol-5-yl)-ethyl]-ureaHCID 25174491—

Reaction Steps

This compound is prepared analogously to Intermediate E1 (described in preparation of intermediates section) by replacing 2-(2-isopropyl-2H-tetrazol-5-yl)-ethylamine hydrochloride (Intermediate D1) with 2-(2-ethyl-2H-tetrazol-5-yl)-ethylamine (Intermediate D2).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08053574B2
Source datasetuspto-grants-2011_11
ORD IDord-3756083e3e7943c4b45912e910617685
Source noteuspto-grants-2011_11