Hydrochloric Acid → HCID 59437570, compound

HRID 555991Notes

Reaction equation

HRID 555991 reaction equation
C(OC(=O)[NH:7][CH2:8][CH2:9][C:10]1[N:14]([CH3:15])[N:13]=[N:12][N:11]=1)(C)(C)C.Cl.O1CCOCC1>C(Cl)Cl>[CH3:15][N:14]1[C:10]([CH2:9][CH2:8][NH2:7])=[N:11][N:12]=[N:13]1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 312751,4-DioxaneHCID 66986287HCID 66986287, compound

Product 1

HCID 59437570HCID 59437570, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

[2-(1-Methyl-1H-tetrazol-5-yl)-ethyl]-carbamic acid tert-butyl ester (0.204 g, 0.9 mmol) is dissolved in DCM (3.5 ml). To this solution is added 4M HCl in dioxane (0.9 ml, 3.6 mmol) and the reaction mixture is stirred at room temperature overnight. The solvent is removed in vacuo to afford the title compound as the hydrochloride salt.

Workup

  1. customThe solvent is removed in vacuo

Sources & evidence

ORD record
ord-2ff71f5703b64eafbb3597488117913f
Source dataset
uspto-grants-2011_11
Patent number
US08053574B2

Reaction notes

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