反应详情

Add 1,8-Bis(3-chloropropionamido)anthraquinone (compound 4, 0.42 g, 1.0 mmol) with pyridine (0.5 ml) and N-ethylmethylamine (0.6 ml, 6 mmole), dissolved in 20 ml dehydrated THF. The mixture is reacted in a mini-reactor. The reaction temperature is 70-80° C. in an oil bath and the reaction time is 6 hours. The reacted mixture is poured into 50 ml ice water, extracted with ethyl acetate and recrystallized from ethanol to get compound 4k.

1. dissolutiondissolved in 20 ml
2. customThe mixture is reacted in a mini-reactor
3. customThe reaction temperature is 70-80° C. in an oil bath
4. extractionextracted with ethyl acetate
5. customrecrystallized from ethanol