HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → (S)-methyl 2-amino-4-bromobutanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Methanol | HCID 887 | — |
| Reactant | (S)-(+)-2-Amino-4-bromobutyric Acid Hydrobromide | HCID 2733672 | — |
| Product | (S)-methyl 2-amino-4-bromobutanoate | HCID 1512645 | — |
Reaction Steps
A solution of (5)-(+)-2-amino-4-bromobutyric acid hydrobromide salt (5 g) in a solution of 3M HCl in MeOH (57 mL) was refluxed for 20 h. The reaction mixture was evaporated off to afford after HV drying the desired compound as a brown oil (3.97 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08058263B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-f70935b2fcb34a9283e40c5912fa8038 |
| Source note | uspto-grants-2011_11 |