HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Bromide → AZD-3199 dihydrobromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | Azd-3199 | HCID 16035068 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | AZD-3199 dihydrobromide | HCID 25031637 | — |
Reaction Steps
N-[2-(Diethylamino)ethyl]-N-(2-{[2-(4-hydroxy-2-oxo-2,3-dihydro-1,3-benzothiazol-7-yl)ethyl]amino}ethyl)-3-[2-(1-naphthyl)ethoxy]propanamide (0.052 g) was dissolved in ethanol (1.5 mL) and treated with 48% hydrobromic acid (21 μl). The white solid dihydrobromide salt (0.058 g) was collected by filtration.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08058294B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-567d07093cb64a0b8aad4dfedf69730b |
| Source note | uspto-grants-2011_11 |