4-Fluorobenzaldehyde → HCID 11653873, compound

HRID 557104Notes

Reaction equation

HRID 557104 reaction equation
[F:1][C:2]1[CH:9]=[CH:8][C:5]([CH:6]=O)=[CH:4][CH:3]=1.C([CH2:13][S:14]([CH2:17][S:18]([CH2:21][C:22](O)=O)(=[O:20])=[O:19])(=[O:16])=[O:15])(O)=O>C(O)(=O)C>[F:1][C:2]1[CH:9]=[CH:8][C:5](/[CH:6]=[CH:13]/[S:14]([CH2:17][S:18](/[CH:21]=[CH:22]/[C:5]2[CH:8]=[CH:9][C:2]([F:1])=[CH:3][CH:4]=2)(=[O:20])=[O:19])(=[O:16])=[O:15])=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 680234-FluorobenzaldehydeHCID 2252641Acetic acid, 2,2'-[methylenebis(sulfonyl)]bis-

Product 1

HCID 11653873HCID 11653873, compoundYield 74%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

A solution of 4-fluorobenzaldehyde (2 mmol) and carboxymethane-sulfonylmethanesulfonyl-acetic acid (1 mmol) in acetic acid (10 mL) was subjected to General Procedure 1, to yield the title compound in 74% yield. m.p. 183-185° C.

Sources & evidence

ORD record
ord-23ea146504ed4137b523b4d16b5d3bb6
Source dataset
uspto-grants-2011_11
Patent number
US08058313B2

Reaction notes

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