HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-Dimethoxy-4-hydroxybenzaldehyde → 4-((1E)-2-(((E)-4-hydroxy-2,6-dimethoxystyrylsulfonyl)methylsulfonyl)vinyl)-3,5-dimethoxyphenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-Dimethoxy-4-hydroxybenzaldehyde | HCID 529894 | — |
| Reactant | Acetic acid, 2,2'-[methylenebis(sulfonyl)]bis- | HCID 2252641 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 4-((1E)-2-(((E)-4-hydroxy-2,6-dimethoxystyrylsulfonyl)methylsulfonyl)vinyl)-3,5-dimethoxyphenol | HCID 11620311 | 62% |
Reaction Steps
A solution of 4-hydroxy-2,6-dimethoxybenzaldehyde (2 mmol) and carboxymethane-sulfonylmethanesulfonyl-acetic acid (1 mmol) in acetic acid (10 mL) was subjected to General Procedure 1, to yield the title compound in 62% yield. m.p. 148-150° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08058313B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-9709759630ff470e8f2d8eea6e19f9a0 |
| Source note | uspto-grants-2011_11 |