Isovanillin → HCID 86761436, compound

HRID 557108Notes

Reaction equation

HRID 557108 reaction equation
[OH:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[O:10][CH3:11])[CH:5]=O.C([CH2:15][S:16]([CH2:19][S:20]([CH2:23][C:24](O)=O)(=[O:22])=[O:21])(=[O:18])=[O:17])(O)=O>C(O)(=O)C>[OH:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[O:10][CH3:11])/[CH:5]=[CH:15]/[S:16]([CH2:19][S:20](/[CH:23]=[CH:24]/[C:4]1[CH:7]=[CH:8][C:9]([O:10][CH3:11])=[C:2]([OH:1])[CH:3]=1)(=[O:21])=[O:22])(=[O:17])=[O:18]

Participants

4

Reactant 2

HCID 12127IsovanillinHCID 2252641Acetic acid, 2,2'-[methylenebis(sulfonyl)]bis-

Product 1

HCID 86761436HCID 86761436, compoundYield 62%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

A solution of 3-hydroxy-4-methoxybenzaldehyde (2 mmol) and carboxymethane-sulfonylmethanesulfonyl-acetic acid (1 mmol) in acetic acid (10 mL) was subjected to General Procedure 1, to yield the title compound in 62% yield. m.p. 148-150° C.

Sources & evidence

ORD record
ord-bffc1ddb31e34525977172f74181c0f2
Source dataset
uspto-grants-2011_11
Patent number
US08058313B2

Reaction notes

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