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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 557119Generated: October 30, 2026

Lawesson's reagent → 4-Quinazolinethiol

https://huagongshe.com/reaction/557119

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLawesson's reagentHCID 87949—
ReactantHCID 178516534HCID 178516534—
ReactantHCID 178518216HCID 178518216—
Product4-QuinazolinethiolHCID 736090—

Reaction Steps

In the next step the carbonyl function of the 1H-quinazolin-4-one derivative, or the 1H-pyrimidin-4-one derivative with a condensed 5-membered heterocyclic ring structure is reacted further e.g. with phosphorous pentasulfide or Lawesson's reagent to yield the 1H-quinazolin-4-thion derivatives, or the 1H-pyrimidin-4-thion one derivatives with a condensed 5-membered heterocyclic ring structure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08058431B2
Source datasetuspto-grants-2011_11
ORD IDord-d7a61baa0ed44b7caf74d42debb58e23
Source noteuspto-grants-2011_11