Ethane, 2-bromo-1,1-diethoxy- → 5-Bromoimidazo[1,2-a]pyridine hydrobromide

Participants

Reaction Steps

Add 2-bromo-1,1-diethoxyethane (3.64 g, 18.48 mmol) to a solution of 6-bromopyridin-2-ylamine (1.0 g, 5.77 mmol) in n-butanol (40 ml). Reflux the reaction overnight, cool. Filtration of the reaction mixture gives 5-bromoimidazo[1,2-a]pyridine hydrobromide as a white solid.

Provenance & Evidence