2,2,2-Trifluoroethanol → 2,2,2-trifluoroethyl 3-oxobutanoate

HRID 557395Notes

Reaction equation

HRID 557395 reaction equation
CC1(C)[O:7][C:6](=O)[CH:5]=[C:4]([CH3:9])[O:3]1.[F:11][C:12]([F:16])([F:15])[CH2:13][OH:14]>>[O:3]=[C:4]([CH3:9])[CH2:5][C:6]([O:14][CH2:13][C:12]([F:16])([F:15])[F:11])=[O:7]

Participants

3

Reactant 2

HCID 64092,2,2-TrifluoroethanolHCID 793682,2,6-Trimethyl-4H-1,3-dioxin-4-one

Product 1

HCID 105836122,2,2-trifluoroethyl 3-oxobutanoate

Procedure

The title compound is prepared in analogy to example 3 (stage 3a) starting from 2,2,6-trimethyl-1,3-dioxin-4-one and 2,2,2-trifluoroethanol.

Sources & evidence

ORD record
ord-2d0c83ec900247f48da9f6750c4d97e7
Source dataset
uspto-grants-2011_11
Patent number
US08058447B2

Reaction notes

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