HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butanol → tert-Butyl 2-chloro-2-oxoacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butanol | HCID 6386 | — |
| Reactant | Oxalyl chloride | HCID 65578 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | tert-Butyl 2-chloro-2-oxoacetate | HCID 11126621 | — |
Reaction Steps
Oxalyl chloride (232 μL, 2.8 mmol) and t-butyl alcohol (228 μL) were combined in ether (6.7 mL) under nitrogen at 0° C. The resulting mixture was stirred for 30 minutes at room temperature. The solvent was evaporated under vacuum to form Compound 34.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09433598B2 |
| Source dataset | uspto-grants-2016_09 |
| ORD ID | ord-d872591027264a99a4c357f08f23f73a |
| Source note | uspto-grants-2016_09 |