HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aluminum(III) Chloride → 1-Acetyl-4-phenyl-1,2,3,4-tetrahydro-2,2,4-trimethylquinoline-6-carboxylic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aluminum(III) Chloride | HCID 6451240 | — |
| Reactant | 1-Acetyl-1,2-dihydro-2,2,4-trimethylquinoline-6-carboxylic acid methyl ester | HCID 66992478 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | 1-Acetyl-4-phenyl-1,2,3,4-tetrahydro-2,2,4-trimethylquinoline-6-carboxylic acid methyl ester | HCID 66992476 | — |
Reaction Steps
Friedel-Crafts alkylation of benzene (60 ml) with 1-acetyl-1,2-dihydro-2,2,4-trimethylquinoline-6-carboxylic acid methyl ester (2.3 g) in the presence of AlCl3 (4.4 g) was performed according to the method described in example 3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08058441B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-7e46ca645eb5454e989cb32740c6a05b |
| Source note | uspto-grants-2011_11 |