Glycol monoethyl ether → HCID 66992385, compound

HRID 557609Notes

Reaction equation

HRID 557609 reaction equation
[CH2:1]([O:3][CH2:4][CH2:5][OH:6])[CH3:2].[C:7]([N:10]1[C:19]2[C:14](=[CH:15][C:16]([NH:20][C:21](=[O:24])[CH:22]=[CH2:23])=[CH:17][CH:18]=2)[C:13]([C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)([CH3:25])[CH2:12][C:11]1([CH3:33])[CH3:32])(=[O:9])[CH3:8]>C1COCC1>[C:7]([N:10]1[C:19]2[C:14](=[CH:15][C:16]([NH:20][C:21]([CH2:22][CH2:23][O:6][CH2:5][CH2:4][O:3][CH2:1][CH3:2])=[O:24])=[CH:17][CH:18]=2)[C:13]([C:26]2[CH:27]=[CH:28][CH:29]=[CH:30][CH:31]=2)([CH3:25])[CH2:12][C:11]1([CH3:33])[CH3:32])(=[O:9])[CH3:8]

Participants

4

Reactant 2

HCID 8076Glycol monoethyl etherHCID 17962870HCID 17962870, compound

Product 1

HCID 66992385HCID 66992385, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Michael addition of 2-ethoxyethanol (19 mg) and 1-acetyl-6-acryloylamino-4-phenyl-1,2,3,4-tetrahydro-2,2,4-trimethylquinoline (8 mg) in THF (1 mL) was performed according to the method described in example 65.

Sources & evidence

ORD record
ord-517eda77215b4725a6acebad88445e2d
Source dataset
uspto-grants-2011_11
Patent number
US08058441B2

Reaction notes

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