反应详情

温度

100 °C

Followed Scheme 2, Step 1 starting from 4-cyanophenylboronic acid and 2,4-dichloro-6-methoxyquinoline, where the solvent used was DMF, and the catalyst used was Pd(PPh3)4. The mixture was heated to 100° C. for 3 h, allowed to cool, and then poured into ice water. The resulting solid was isolated by filtration, washed with water, and dried followed by recrystallization from methanol to give the desired product.

1. temperatureto cool
2. customThe resulting solid was isolated by filtration
3. washwashed with water
4. customdried
5. customfollowed by recrystallization from methanol