Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1-Tetralone | HCID 10724 | — |
| Reactant | 1,3-Diethyl 2-oxopropanedioate | HCID 69105 | — |
| Product | HCID 10495917 | HCID 10495917 | 70.4% |
Reaction Steps
A mixture of the required tetralone (0.01 mol) and diethyl mesoxalate (0.014 mol) was heated at 100° C. for 12 h. After cooling, the reaction mixture was purified by silica gel chromatography, eluting with cyclohexane/ethyl acetate (8/2), to give the white crystals. Yield 70.4%. ESI-MS: m/z 321.1 (M+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08063047B2 |
|---|
| Source dataset | uspto-grants-2011_11 |
|---|
| ORD ID | ord-ffd927e953704d8191ce31b2e28c45f4 |
|---|
| Source note | uspto-grants-2011_11 |
|---|
