Ethylamine hydrochloride → N-ethyl-4-methoxy-3-[(E)-2-(4-trifluoromethoxyphenyl)-vinyl]benzamide
Reaction equation
[CH3:1][O:2][C:3]1[CH:11]=[CH:10][C:6]([C:7]([OH:9])=O)=[CH:5][C:4]=1/[CH:12]=[CH:13]/[C:14]1[CH:19]=[CH:18][C:17]([O:20][C:21]([F:24])([F:23])[F:22])=[CH:16][CH:15]=1.Cl.[CH2:26]([NH2:28])[CH3:27]>>[CH2:26]([NH:28][C:7](=[O:9])[C:6]1[CH:10]=[CH:11][C:3]([O:2][CH3:1])=[C:4](/[CH:12]=[CH:13]/[C:14]2[CH:15]=[CH:16][C:17]([O:20][C:21]([F:22])([F:24])[F:23])=[CH:18][CH:19]=2)[CH:5]=1)[CH3:27]Participants
3
Procedure
The captioned compound was synthesized from 4-methoxy-3-[(E)-2-(4-trifluoromethoxyphenyl)vinyl]benzoic acid and ethylamine hydrochloride in accordance with the same procedure as in the methods described in step C of Example 1-2-3.
Sources & evidence
- ORD record
- ord-d43ad75fae13475ca5d114473dbf17d2
- Source dataset
- uspto-grants-2011_11
- Patent number
- US08063046B2
Reaction notes
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