2-Amino-2-thioxoethyl 2,2-dimethylpropanoate → 2,2-Dimethylpropionic acid 4-[3-(4-fluorophenyl)-1,9-dimethyl-2-oxo-2,9-dihydro-1H-pyrido[2,3-b]indol-6-yl]-thiazol-2-ylmethyl ester

Participants

Role	Name	HCID	Charge
Reactant	2-Amino-2-thioxoethyl 2,2-dimethylpropanoate	HCID 2782113	—
Reactant	6-(2-Bromoacetyl)-3-(4-fluorophenyl)-1,9-dimethyl-1,9-dihydropyrido[2,3-b]indol-2-one	HCID 86623951	—
Product	2,2-Dimethylpropionic acid 4-[3-(4-fluorophenyl)-1,9-dimethyl-2-oxo-2,9-dihydro-1H-pyrido[2,3-b]indol-6-yl]-thiazol-2-ylmethyl ester	HCID 66997878	—

Reaction Steps

The process is carried out as indicated in Example 3 above, with compound B 6-(2-bromoacetyl)-3-(4-fluorophenyl)-1,9-dimethyl-1,9-dihydropyrido[2,3-b]indol-2-one and 2-amino-2-thioxoethyl pivalate

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08063061B2
Source dataset	uspto-grants-2011_11
ORD ID	ord-1ad4a7fcd7154ebebf54cae4c7625c6b
Source note	uspto-grants-2011_11