Iodoethane → 3-(4-Bromophenyl)-6-(1-ethyl-1H-pyrazol-3-yl)-1,9-dimethyl-1,9-dihydropyrido[2,3-b]indol-2-one

HRID 559180Notes

Reaction equation

HRID 559180 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:26](=[O:27])[N:25]([CH3:28])[C:11]3[N:12]([CH3:24])[C:13]4[C:18]([C:10]=3[CH:9]=2)=[CH:17][C:16]([C:19]2[NH:20][N:21]=[CH:22][CH:23]=2)=[CH:15][CH:14]=4)=[CH:4][CH:3]=1.I[CH2:30][CH3:31]>>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:26](=[O:27])[N:25]([CH3:28])[C:11]3[N:12]([CH3:24])[C:13]4[C:18]([C:10]=3[CH:9]=2)=[CH:17][C:16]([C:19]2[CH:23]=[CH:22][N:21]([CH2:30][CH3:31])[N:20]=2)=[CH:15][CH:14]=4)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 6340IodoethaneHCID 669982413-(4-Bromophenyl)-1,9-dimethyl-6-(2H-pyrazol-3-yl)-1,9-dihydropyrido[2,3-b]indol-2-one

Product 1

HCID 162262643-(4-Bromophenyl)-6-(1-ethyl-1H-pyrazol-3-yl)-1,9-dimethyl-1,9-dihydropyrido[2,3-b]indol-2-one

Procedure

The process is carried out as indicated in Example 36 above, using 3-(4-bromophenyl)-1,9-dimethyl-6-(2H-pyrazol-3-yl)-1,9-dihydropyrido[2,3-b]indol-2-one from Example 60 above and iodoethane.

Sources & evidence

ORD record
ord-9696e1c4a533470584247d2452f5dd92
Source dataset
uspto-grants-2011_11
Patent number
US08063061B2

Reaction notes

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