Hydrazine hydrate (1:1) → HCID 178483145, compound

HRID 559198Notes

Reaction equation

HRID 559198 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[C:9]1[C:31](=O)[N:30]([CH3:33])[C:12]2[N:13]([CH3:29])[C:14]3[C:19]([C:11]=2[CH:10]=1)=[CH:18][C:17]([C:20](=O)[CH2:21][C:22](=O)[CH2:23][N:24]([CH3:26])[CH3:25])=[CH:16][CH:15]=3.[OH2:34].[NH2:35][NH2:36]>>[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[C:9]1[C:31](=[O:34])[N:30]([CH3:33])[C:12]2[N:13]([CH3:29])[C:14]3[C:19]([C:11]=2[CH:10]=1)=[CH:18][C:17]([C:20]1[NH:35][N:36]=[C:22]([CH2:23][N:24]([CH3:26])[CH3:25])[CH:21]=1)=[CH:16][CH:15]=3

Participants

3

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 669983051-[3-(2,4-Dichlorophenyl)-1,9-dimethyl-2-oxo-2,9-dihydro-1H-pyrido[2,3-b]indol-6-yl]-4-dimethylaminobutane-1,3-dione

Product 1

HCID 178483145HCID 178483145, compound

Procedure

The process is carried out as in Example 43 above, with compound A 1-[3-(2,4-dichlorophenyl)-1,9-dimethyl-2-oxo-2,9-dihydro-1H-pyrido[2,3-b]indol-6-yl]-4-dimethylaminobutane-1,3-dione and hydrazine monohydrate.

Sources & evidence

ORD record
ord-37ffd088ff4c4480a06e69a1450ddaaa
Source dataset
uspto-grants-2011_11
Patent number
US08063061B2

Reaction notes

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