2-Bromoethyl ethyl ether → HCID 66997914, compound

HRID 559227Notes

Reaction equation

HRID 559227 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[C:9]1[C:30](=[O:31])[N:29]([CH3:32])[C:12]2[N:13]([CH3:28])[C:14]3[C:19]([C:11]=2[CH:10]=1)=[CH:18][C:17]([C:20]1[CH:24]=[CH:23][N:22]([CH2:25][CH2:26][OH:27])[N:21]=1)=[CH:16][CH:15]=3.[CH2:33]([O:35][CH2:36][CH2:37]Br)[CH3:34]>>[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[C:9]1[C:30](=[O:31])[N:29]([CH3:32])[C:12]2[N:13]([CH3:28])[C:14]3[C:19]([C:11]=2[CH:10]=1)=[CH:18][C:17]([C:20]1[CH:24]=[CH:23][N:22]([CH2:25][CH2:26][O:27][CH2:34][CH2:33][O:35][CH2:36][CH3:37])[N:21]=1)=[CH:16][CH:15]=3

Participants

3

Reactant 2

HCID 611412-Bromoethyl ethyl etherHCID 66997394HCID 66997394, compound

Product 1

HCID 66997914HCID 66997914, compound

Procedure

The process is carried out as in Example 101 above, with the compound from Example 51, 3-(2,4-dichlorophenyl)-6-[1-(2-hydroxyethyl)-1H-pyrazol-3-yl]-1,9-dimethyl-1,9-dihydropyrido[2,3-b]indol-2-one and 2-bromoethyl ethyl ether.

Sources & evidence

ORD record
ord-0bded5c75f3e451aaea165acd55efab5
Source dataset
uspto-grants-2011_11
Patent number
US08063061B2

Reaction notes

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