Iodoethane → 3-(2,4-Dichlorophenyl)-9-difluoromethyl-6-(1-ethyl-1H-pyrazol-3-yl)-1-methyl-1,9-dihydropyrido[2,3-b]indol-2-one

HRID 559267Notes

Reaction equation

HRID 559267 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[C:9]1[C:29](=[O:30])[N:28]([CH3:31])[C:12]2[N:13]([CH:25]([F:27])[F:26])[C:14]3[C:19]([C:11]=2[CH:10]=1)=[CH:18][C:17]([C:20]1[CH:24]=[CH:23][NH:22][N:21]=1)=[CH:16][CH:15]=3.I[CH2:33][CH3:34]>>[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[CH:5]=[CH:4][C:3]=1[C:9]1[C:29](=[O:30])[N:28]([CH3:31])[C:12]2[N:13]([CH:25]([F:26])[F:27])[C:14]3[C:19]([C:11]=2[CH:10]=1)=[CH:18][C:17]([C:20]1[CH:24]=[CH:23][N:22]([CH2:33][CH3:34])[N:21]=1)=[CH:16][CH:15]=3

Participants

3

Reactant 2

HCID 6340IodoethaneHCID 178481368HCID 178481368, compound

Product 1

HCID 669973573-(2,4-Dichlorophenyl)-9-difluoromethyl-6-(1-ethyl-1H-pyrazol-3-yl)-1-methyl-1,9-dihydropyrido[2,3-b]indol-2-one

Procedure

The process is carried out as indicated in Example 110 above, with compound A, 3-(2,4-dichlorophenyl)-9-difluoromethyl-1-methyl-6-(1H-pyrazol-3-yl)-1,9-dihydropyrido[2,3-b]indol-2-one, and iodoethane.

Sources & evidence

ORD record
ord-6c4513e9b31a44a2a1ff37b285298be3
Source dataset
uspto-grants-2011_11
Patent number
US08063061B2

Reaction notes

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