反应详情

温度

75 °C

5 g of crude (I) wherein n is 1 were loaded in a reactor together with 30 ml of ethyl acetate and the suspension was stirred while heating to 75° C. until complete dissolution of the solid. 15 ml of n-heptane were added and the solution was allowed to reach RT. The suspension was cooled down to 5° C. for 2 hours, filtered and dried under vacuum. A white solid, the so-called Form A, was obtained (3.6 g, 72% yield).

1. customto reach RT
2. temperatureThe suspension was cooled down to 5° C. for 2 hours
3. filtrationfiltered
4. customdried under vacuum
5. customA white solid, the so-called Form A, was obtained (3.6 g, 72% yield)