反应详情

In analogy to example 1, step 3,1-benzenesulfonyl-4-(4-bromo-phenyl)-3-phenyl-imlidazolidin-2-one (example 1, step 2) was reacted with 2,5-dimethylphenylboronic acid in the presence of dichloro[1,1′-bis(diphenylphosphino)ferrocene]palladium dichloromethane adduct and sodium carbonate in dioxane/water to give 1-benzenesulfonyl-4-(2′,5′-dimethyl-biphenyl 4-yl)-3-phenyl-imidazolidin-2-one as a colorless solid. MS: 483.2 ([M+H]+)