HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → 1-Benzenesulfonyl-4-(2',5'-dimethyl-biphenyl 4-yl)-3-phenyl-imidazolidin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | (2,5-Dimethylphenyl)boronic acid | HCID 2734347 | — |
| Reactant | 1-Benzenesulfonyl-4-(4-bromo-phenyl)-3-phenyl-imidazolidin-2-one | HCID 67001220 | — |
| Catalyst | HCID 178418807 | HCID 178418807 | — |
| Solvent | 1,4-Dioxane--water (1/1) | HCID 21886435 | — |
| Product | 1-Benzenesulfonyl-4-(2',5'-dimethyl-biphenyl 4-yl)-3-phenyl-imidazolidin-2-one | HCID 44547591 | — |
Reaction Steps
In analogy to example 1, step 3,1-benzenesulfonyl-4-(4-bromo-phenyl)-3-phenyl-imlidazolidin-2-one (example 1, step 2) was reacted with 2,5-dimethylphenylboronic acid in the presence of dichloro[1,1′-bis(diphenylphosphino)ferrocene]palladium dichloromethane adduct and sodium carbonate in dioxane/water to give 1-benzenesulfonyl-4-(2′,5′-dimethyl-biphenyl 4-yl)-3-phenyl-imidazolidin-2-one as a colorless solid. MS: 483.2 ([M+H]+)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08063088B2 |
| Source dataset | uspto-grants-2011_11 |
| ORD ID | ord-c60e8d07a3d74951875ac3068e4b08f2 |
| Source note | uspto-grants-2011_11 |