Pyrrolidine → 1-(Pyrrolidin-1-yl)cyclopropanecarbonitrile

HRID 560190Notes

Reaction equation

HRID 560190 reaction equation
[N:1]1([C:6]2([C:10]#[N:11])[CH2:9]O[CH2:7]2)[CH2:5][CH2:4][CH2:3][CH2:2]1.C(OC1(O[Si](C)(C)C)CC1)C.N1CCCC1>>[N:1]1([C:6]2([C:10]#[N:11])[CH2:9][CH2:7]2)[CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

4

Reactant 3

HCID 31268PyrrolidineHCID 2734686(1-Ethoxycyclopropoxy)trimethylsilaneHCID 591979193-Cyano-3-(pyrrolidin-1-YL)oxetane

Product 1

HCID 223251461-(Pyrrolidin-1-yl)cyclopropanecarbonitrile

Procedure

The title compound, colorless liquid, was prepared in accordance with the general method of intermediate A from ((1-ethoxycyclopropyl)oxy)trimethylsilane and pyrrolidine.

Sources & evidence

ORD record
ord-4e1c416f4dad49768d7c7b05f48e1ec6
Source dataset
uspto-grants-2011_11
Patent number
US08063098B2

Reaction notes

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