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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 560193Generated: October 25, 2026

Cyclobutanone → 1-Pyrrolidin-1-yl-cyclobutanecarbonitrile

https://huagongshe.com/reaction/560193

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclobutanoneHCID 14496—
ReactantPyrrolidineHCID 31268—
Reactant3-Cyano-3-(pyrrolidin-1-YL)oxetaneHCID 59197919—
Product1-Pyrrolidin-1-yl-cyclobutanecarbonitrileHCID 43802773—

Reaction Steps

The title compound, colorless liquid, MS: m/e=151.1 [(M+H)+], was prepared in accordance with the general method of intermediate A from cyclobutanone and pyrrolidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08063098B2
Source datasetuspto-grants-2011_11
ORD IDord-017087a471024d1da670f79899c52229
Source noteuspto-grants-2011_11