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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 560203Generated: October 25, 2026

Dimethylamine, hydrochloride → 1-(Dimethylamino)cyclobutanecarbonitrile

https://huagongshe.com/reaction/560203

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylamine, hydrochlorideHCID 10473—
ReactantCyclobutanoneHCID 14496—
Reactant3-Cyano-3-(pyrrolidin-1-YL)oxetaneHCID 59197919—
Product1-(Dimethylamino)cyclobutanecarbonitrileHCID 10749177—

Reaction Steps

The title compound, colorless liquid, MS: m/e=125.1 [(M+H)+], was prepared in accordance with the general method of intermediate A from cyclobutanone and dimethylamine hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08063098B2
Source datasetuspto-grants-2011_11
ORD IDord-4f735b5783644926bcbbb539831a6f88
Source noteuspto-grants-2011_11