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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 560250Generated: October 30, 2026

Cyclopropanecarbothioamide → 2-Cyclopropyl-5-(3-fluoro-phenyl)-thiazole-4-carboxylic Acid Methyl Ester

https://huagongshe.com/reaction/560250

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopropanecarbothioamideHCID 22140884—
ReactantMethyl 3-chloro-3-(3-fluorophenyl)-2-oxopropanoateHCID 57437155—
Product2-Cyclopropyl-5-(3-fluoro-phenyl)-thiazole-4-carboxylic Acid Methyl EsterHCID 66866670—

Reaction Steps

prepared by reaction of 3-chloro-3-(3-fluoro-phenyl)-2-oxo-propionic acid methyl ester with cyclopropanecarbothioic acid amide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08063099B2
Source datasetuspto-grants-2011_11
ORD IDord-4f04746d807d4fec974d64fecc992f78
Source noteuspto-grants-2011_11