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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 560251Generated: October 30, 2026

Cyclopropanecarbothioamide → 2-Cyclopropyl-5-(3-fluoro-4-methyl-phenyl)-thiazole-4-carboxylic Acid Methyl Ester

https://huagongshe.com/reaction/560251

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopropanecarbothioamideHCID 22140884—
Reactant3-Chloro-3-(3-fluoro-4-methyl-phenyl)-2-oxo-propionic acid methyl esterHCID 64898287—
Product2-Cyclopropyl-5-(3-fluoro-4-methyl-phenyl)-thiazole-4-carboxylic Acid Methyl EsterHCID 66865662—

Reaction Steps

prepared by reaction of 3-chloro-3-(3-fluoro-4-methyl-phenyl)-2-oxo-propionic acid methyl ester with cyclopropanecarbothioic acid amide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08063099B2
Source datasetuspto-grants-2011_11
ORD IDord-2860d0ba78b647c19bf8f27ba25115a1
Source noteuspto-grants-2011_11