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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 560253Generated: October 29, 2026

Thiourea → Methyl 2-amino-5-(3-fluorophenyl)-1,3-thiazole-4-carboxylate

https://huagongshe.com/reaction/560253

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThioureaHCID 2723790—
ReactantMethyl 3-chloro-3-(3-fluorophenyl)-2-oxopropanoateHCID 57437155—
ProductMethyl 2-amino-5-(3-fluorophenyl)-1,3-thiazole-4-carboxylateHCID 2783208—

Reaction Steps

prepared by reaction of 3-chloro-3-(3-fluoro-phenyl)-2-oxo-propionic acid methyl ester with thiourea. LC-MS: tR=0.78 min; [M+H]+=252.9.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08063099B2
Source datasetuspto-grants-2011_11
ORD IDord-b9726f3b8a294c6d97c510768221a605
Source noteuspto-grants-2011_11